Australian freestyle swimmer Shayna Jack tested positive to the banned substance Ligandrol in late June, before competing at the world swimming championships in South Korea this month. Jack said she did not knowingly take Ligandrol but noted it could be found in contaminated supplements. Ligandrol can help repair and build muscles. While it has been studied as a treatment for cancer and other conditions where patients experience muscle weakness and wastage, it is banned for use by professional athletes. So how long has this drug been around, and how does it work? History of Ligandrol Ligandrol, which is also known by the development codes LGD-4033 and VK5211 and the name Anabolicum, was initially developed by the company Ligand Pharmaceuticals in the United States. It was patented in 2009.